RESEARCH HIGHLIGHT - Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs

The aggregation of the protein α-synuclein (α-syn) leads to different synucleinopathies. IMPRIND Partner CNRS showed that structurally distinct fibrillar

α-syn polymorphs trigger either Parkinson’s disease or multiple system atrophy hallmarks in vivo.

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This project receives funding from the Innovative Medicines Initiative 2 Joint Undertaking ( under grant agreement No 116060. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.

This work is supported by the Swiss State Secretariat for Education‚ Research and Innovation (SERI) under contract number 17.00038.

The opinions expressed and arguments employed herein do not necessarily reflect the official views of these funding bodies.

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